LC-qTOF, also known as liquid chromatography-quadrupole time-of-flight, is an advanced analytical technique used in various scientific fields such as chemistry, pharmaceuticals, and environmental science.
In simple terms, LC-qTOF helps scientists analyze and identify the chemical makeup of different substances. It combines two key processes: liquid chromatography, which separates the components of a mixture, and quadrupole time-of-flight mass spectrometry, which measures the mass and charge of those components.
LC-qTOF is also known for its high-resolution mass accuracy. High-resolution mass accuracy refers to the precision with which the mass of a compound is determined. It is a critical feature of LC-qTOF that allows scientists to obtain precise and accurate molecular weight measurements of the components in a sample. The advantage of high-resolution mass accuracy is that it enables scientists to differentiate between compounds with similar mass values but different molecular compositions enabling them to confidently identify drugs and other chemicals in complex biological samples.